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1

The design of dipeptide helical mimetics: The synthesis, tachykinin receptor affinity and conformational analysis of 1,1,6-trisubstituted indanes

David C. Horwell, William Howson, Giles S. Ratcliffe, Henriëtte M.G. Willems

Journal:

Bioorganic & Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 944 KB

english, 1996

2

Design of a structural motif ‘dendroid’ to mimic protein: Protein interactions via intramolecular self-organisation

Joanne V. Allen, David C. Horwell, Julia A.H. Lainton, Jacqueline A. O'Neill, Giles S. Ratcliffe

Journal:

International Journal of Peptide Research and Therapeutics

Year:

1998

Language:

english

File:

PDF, 125 KB

english, 1998

3

Responding to the increased genetic risk associated with customary consanguineous marriage among minority ethnic populations: lessons from local innovations in England

Salway, Sarah, Ali, Parveen, Ratcliffe, Giles, Such, Elizabeth, Khan, Nasaim, Kingston, Helen, Quarrell, Oliver

Journal:

Journal of Community Genetics

Year:

2016

Language:

english

File:

PDF, 390 KB

english, 2016

4

HYPOTHALAMIC-PITUITARY-ADRENOCORTICAL FUNCTION IN ADULTS WITH DOWN'S SYNDROME

J. C. MURDOCH, C. A. GILES, J. K. GRANT, J. G. RATCLIFFE

Journal:

Journal of Intellectual Disability Research

Year:

1979

Language:

english

File:

PDF, 322 KB

english, 1979

5

Nursing Home Registered Nursesʼ and Licensed Practical Nursesʼ Knowledge of Causes of Falls

Gray-Miceli, Deanna, de Cordova, Pamela B., Crane, Giles L., Quigley, Patricia, Ratcliffe, Sarah J.

Journal:

Journal of Nursing Care Quality

Year:

2016

Language:

english

File:

PDF, 99 KB

english, 2016

6

Chemical Shift Imaging with Continuously Flowing Hyperpolarized Xenon for the Characterization of Materials

Igor L Moudrakovski, Stephen Lang, Christopher I Ratcliffe, Benoit Simard, Giles Santyr, John A Ripmeester

Journal:

Journal of Magnetic Resonance

Year:

2000

Language:

english

File:

PDF, 212 KB

english, 2000

7

Increasing the spin-lattice relaxation time of hyperpolarized xenon ice at 4.2 K

Lang, Stephen, Moudrakovski, Igor L., Ratcliffe, Christopher I., Ripmeester, John A., Santyr, Giles

Journal:

Applied Physics Letters

Year:

2002

Language:

english

File:

PDF, 281 KB

english, 2002

8

Hexon-modified Recombinant E1-deleted Adenovirus Vectors as Dual Specificity Vaccine Carriers for Influenza Virus

Zhou, Dongming, Wu, Te-Lang, Emmer, Kristel L, Kurupati, Raj, Tuyishime, Steven, Li, Yan, Giles-Davis, Wynetta, Zhou, Xiangyang, Xiang, Zhiquan, Liu, Qin, Ratcliffe, Sarah J, Ertl, Hildegund CJ

Journal:

Molecular Therapy

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

9

Quantitative Structure-Activity Relationships (QSARs) of N-Terminus Fragments of NK1 Tachykinin Antagonists: A Comparison of Classical QSARs and Three-Dimensional QSARs from Similarity Matrixes

Horwell, David C., Howson, William, Higginbottom, Michael, Naylor, Dorica, Ratcliffe, Giles S., Williams, Sophie

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 2.39 MB

english, 1995

10

Coatings for optical pumping cells and short-term storage of hyperpolarized xenon

Breeze, Steven R., Lang, Stephen, Moudrakovski, Igor, Ratcliffe, Chris I., Ripmeester, John A., Santyr, Giles, Simard, Benoit, Zuger, Irene

Journal:

Journal of Applied Physics

Year:

2000

Language:

english

File:

PDF, 286 KB

english, 2000

11

Adolescent confidence in immunisation: Assessing and comparing attitudes of adolescents and adults

Wang, Bing, Giles, Lynne, Afzali, Hossein Haji Ali, Clarke, Michelle, Ratcliffe, Julie, Chen, Gang, Marshall, Helen

Journal:

Year:

2016

Language:

english

File:

PDF, 417 KB

english, 2016

12

The design of a dipeptide library for screening at peptide receptor sites

David C. Horwell, William Howson, Giles S. Ratcliffe, David C. Rees

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 321 KB

english, 1993

13

Design of a structural motif ‘dendroid’ to mimic protein: Protein interactions via intramolecular self-organisation

Joanne V. Allen, David C. Horwell, Julia A. H. Lainton, Jacqueline A. O'Neill, Giles S. Ratcliffe

Journal:

International Journal of Peptide Research and Therapeutics

Year:

1998

Language:

english

File:

PDF, 267 KB

english, 1998

14

Continuous Flow NMR with Hyperpolarized Xenon for the Characterization of Materials and Processes †

Moudrakovski, Igor L., Nossov, Andrej, Lang, Stephen, Breeze, Steven R., Ratcliffe, Christopher I., Simard, Benoit, Santyr, Giles, Ripmeester, John A.

Journal:

Chemistry of Materials

Year:

2000

Language:

english

File:

PDF, 52 KB

english, 2000

15

The design of dipeptide helical mimetics: the synthesis and biological activity of trisubstituted indanes

David C Horwell, William Howson, Giles Ratcliffe, Henriette Willems

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 1.20 MB

english, 1994

16

The use of heterocycles for the conformational restriction of biologically active peptoids

David C. Horwell, Russell A. Lewthwaite, Martyn C. Pritchard, Giles S. Ratcliffe, J. Ronald Rubin

Journal:

Year:

1998

Language:

english

File:

PDF, 914 KB

english, 1998

17

intermetallic compound

Christovam, D. S., Giles, C., Mendonça-Ferreira, L., Leão, J., Ratcliff, W., Lynn, J. W., Ramos, S., Hering, E. N., Hidaka, H., Baggio-Saitovich, E., Fisk, Z., Pagliuso, P. G., Adriano, C.

Journal:

Physical Review B

Year:

2019

Language:

english

File:

PDF, 602 KB

english, 2019

18

The design of dipeptide helical mimetics, Part I: the synthesis of 1,6-disubstituted indanes

David C. Horwell, William Howson, William P. Nolan, Giles S. Ratcliffe, David C. Rees, Henriette M.G. Willems

Journal:

Year:

1995

Language:

english

File:

PDF, 661 KB

english, 1995

19

Alanine scan and N-methyl amide derivatives of Ac-bombesin[7-14]. Development of a proposed binding conformation at the neuromedin B (NMB) and gastrin releasing peptide (GRP) receptors

DAVID C. HORWELL, WILLIAM HOWSON, DORICA NAYLOR, SIMON OSBORNE, ROBERT D. PINNOCK, GILES S. RATCLIFFE, NIRMALA SUMAN-CHAUHAN

Journal:

Chemical Biology & Drug Design

Year:

1996

Language:

english

File:

PDF, 2.16 MB

english, 1996

20

Identification of Novel Ligands for the Gabapentin Binding Site on the α 2 δ Subunit of a Calcium Channel and Their Evaluation as Anticonvulsant Agents

Bryans, Justin S., Davies, Natasha, Gee, Nicolas S., Dissanayake, Visaka U. K., Ratcliffe, Giles S., Horwell, David C., Kneen, Clare O., Morrell, Andrew I., Oles, Ryszard J., O'Toole, John C., Perkins

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 187 KB

english, 1998

21

29Si derivatization and nuclear magnetic resonance study of oxygen functionality in coals and coal products

Oliver W. Howarth, Giles S. Ratcliffe, Paul Burchill

Journal:

Year:

1990

Language:

english

File:

PDF, 820 KB

english, 1990

22

The use of a proline ring as a conformational restraint in CCK-B receptor “dipeptoids”.

Christopher I. Fincham, David C. Horwell, Giles S. Ratcliffe, David C. Rees

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1992

Language:

english

File:

PDF, 298 KB

english, 1992

23

Synthesis of Conformationally Constrained Tryptophan Derivatives

Horwell, David C., Nichols, Paul D., Ratcliffe, Giles S., Roberts, Edward

Journal:

Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 716 KB

english, 1994

24

Adenovirus vector-induced immune responses in nonhuman primates: responses to prime boost regimens

Tatsis, N., Lasaro, M. O., Lin, S.-W., Xiang, Z. Q., Zhou, D., DiMenna, L., Li, H., Bian, A., Abdulla, S., Li, Y., Giles-Davis, W., Engram, J., Ratcliffe, S. J., Silvestri, G., Ertl, H. C., Betts, M.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 206 KB

english, 2009

25

The synthesis of 1,6-disubstituted indanes which mimic the orientation of amino acid side-chains in a protein alpha-helix motif.

William P. Nolan, Giles S. Ratcliffe, David C. Rees

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 241 KB

english, 1992

26

The design and synthesis of kappa opioid ligands based on a binding model for kappa agonists

Michael Higginbottom, William Nolan, John O'Toole, Giles S. Ratcliffe, David C. Rees, Edward Roberts

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 349 KB

english, 1993

27

and Ir)

Adriano, C., Giles, C., Bittar, E. M., Coelho, L. N., de Bergevin, F., Mazzoli, C., Paolasini, L., Ratcliff, W., Bindel, R., Lynn, J. W., Fisk, Z., Pagliuso, P. G.

Journal:

Physical Review B

Year:

2010

Language:

english

File:

PDF, 681 KB

english, 2010

28

Solid-state nuclear magnetic resonance studies of sodium and aluminium in coal

Oliver W. Howarth, Giles S. Ratcliffe, Paul Burchill

Journal:

Year:

1987

Language:

english

File:

PDF, 546 KB

english, 1987

29

‘Targeted’ molecular diversity: design and development of non-peptide antagonists for cholecystokinin and tachykinin receptors

David Horwell, Martyn Pritchard, Jennifer Raphy, Giles Ratcliffe

Journal:

Immunopharmacology

Year:

1996

Language:

english

File:

PDF, 313 KB

english, 1996

30

Coatings for optical pumping cells and extending the lifetime of hyperpolarized xenon

Breeze, Steven R., Lang, Stephen, Moudrakovski, Igor, Ratcliffe, Chris I., Ripmeester, John A., Simard, Benoit, Santyr, Giles

Journal:

Journal of Applied Physics

Year:

1999

Language:

english

File:

PDF, 290 KB

english, 1999

31

Adenovirus Vector-Induced Immune Responses in Nonhuman Primates: Responses to Prime Boost Regimens

Tatsis, N., Lasaro, M. O., Lin, S.-W., Xiang, Z. Q., Zhou, D., DiMenna, L., Li, H., Bian, A., Abdulla, S., Li, Y., Giles-Davis, W., Engram, J., Ratcliffe, S. J., Silvestri, G., Ertl, H. C., Betts, M.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 1.50 MB

english, 2009

32

Rationally designed dipeptoid analogs of cholecystokinin. A Free-Wilson/Fujita-Ban analysis of some .alpha.-methyltryptophan derivatives as cholecystokinin-B antagonists

Higginbottom, Michael, Kneen, Clare, Ratcliffe, Giles S.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 745 KB

english, 1992

33

Amide bond replacements incorporated into CCK-B selective "dipeptoids"

Fincham, Christopher I., Higginbottom, Michael, Hill, David R., Horwell, David C., O'Toole, John C., Ratcliffe, Giles S., Rees, David C., Roberts, Edward

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.77 MB

english, 1992

34

Investigation into the preferred conformation of gabapentin for interaction with its binding site on the α2δ subunit of a calcium channel

Justin S. Bryans, Natasha Davies, Nicolas S. Gee, David C. Horwell, Clare O. Kneen, Andrew I. Morrell, Jacqueline A. O'Neill, Giles S. Ratcliffe

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 161 KB

english, 1997

35

An in vitro investigation into conformational aspects of gabapentin

Justin S. Bryans, David C. Horwell, Giles S. Ratcliffe, Jean-Marie Receveur, J.Ronald Rubin

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 261 KB

english, 1999

36

Use of a Dipeptide Chemical Library in the Development of Non-Peptide Tachykinin NK 3 Receptor Selective Antagonists

Boden, Phil, Eden, Jon M., Hodgson, Julie, Horwell, David C., Hughes, John, McKnight, Alexander T., Lewthwaite, Russell A., Pritchard, Martyn C., Raphy, Jenny, Meecham, Ken, Ratcliffe, Giles S., Suman

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 413 KB

english, 1996

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